David Ortiz hit a two-run homer and knocked in three runs to power the Red Sox to an 8-1 victory over the Cardinals in Game One of the World Series at Fenway Park. Ortiz had a grand slam taken away by Cards right fielder Carlos Beltran in the bottom of the second inning. Beltran left the game with a rib contusion following the catch. Mike Napoli had a bases-clearing double in the first inning for Boston, which hosts Game Two on Thursday. Jon Lester struck out eight over seven-and-two-thirds innings of scoreless ball for the win. Adam Wainwright was shelled for five runs in five innings for the loss. Matt Holliday hit a solo homer in the top of the ninth for St. Louis.
The Cardinals and Red Sox will play Game Two of the World Series tonight at Fenway Park. Rookie Michael Wacha will take the mound for St. Louis, while Boston counters with John Lackey. After tonight's game, the teams will travel to St. Louis with an off-day on Friday. The best-of-seven series will resume with Game Three Saturday night at Busch Stadium.