March Madness kicks into high gear today with 16 second-round games in the NCAA Tournament. The first full day begins with Dayton and Ohio State at 12:15 p.m. Eastern in the South Region in Buffalo. Other early games include Wisconsin against American University in the West, Pittsburgh and Colorado in the South, and Harvard against Cincinnati in the East. Top overall seed Florida will face 16th-seeded Albany at 4:10 p.m. in the South Region in Orlando. Defending national champion Louisville faces Manhattan at 9:50 p.m. in the Midwest Region in Orlando. The final game of the night features San Diego State and New Mexico State at 9:57 p.m. in the West Region in Spokane, Washington. Sixteen more second-round games are on tap Friday, including number-one seeds Wichita State, Arizona and Virginia.